Brain Organoid Research

Brain organoids have revolutionized our ability to study human neurological diseases. These 3D models recapitulate key features of brain development and enable research previously impossible with animal models.

Alzheimer's Disease

Patient-derived organoids modeling amyloid plaque formation and tau pathology for drug screening.

Parkinson's Disease

Dopaminergic neuron models for neuroprotective compound testing and disease mechanism studies.

Glioblastoma

Patient tumor organoids for personalized chemotherapy sensitivity testing.

Zika Virus

Infection models demonstrating viral impacts on developing brain tissue.

Liver Toxicity Research

Drug-induced liver injury (DILI) remains a leading cause of drug failure and withdrawal. Human liver models provide superior prediction of hepatotoxicity compared to animal testing.

87%
DILI Prediction Accuracy
30%
Drug Failures Prevented
$2B
Annual Savings Potential

DILI Prediction

Multi-parameter assessment of hepatotoxicity risk using liver-on-chip systems.

NASH Modeling

Non-alcoholic steatohepatitis models for metabolic liver disease therapeutics.

Drug Metabolism

CYP450 enzyme activity and drug-drug interaction prediction.

Cardiac Safety Testing

Cardiotoxicity is the second leading cause of drug withdrawal. Human heart models detect arrhythmia risks that animal models miss, improving drug safety assessment.

QT Prolongation

hERG channel assays and multi-electrode array testing for arrhythmia prediction.

Contractility

Measure cardiac muscle function and force generation in human cardiomyocytes.

Structural Cardiotoxicity

Detect myocardial damage from cancer therapeutics and other compounds.

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In-depth research on organoids, organ-on-chip, and human simulation science

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