COMPANY OVERVIEW
MatTek Corporation, headquartered in Ashland, Massachusetts, is the leading provider of OECD-validated reconstructed human tissue models. Founded in 1985, the company pioneered commercialization of in vitro skin and ocular models, enabling regulatory-accepted alternatives to animal testing for cosmetics, pharmaceuticals, and chemicals.
PRODUCT PORTFOLIO
- EpiDerm: Reconstructed human epidermis for skin irritation/corrosion (OECD TG 431/439)
- EpiDerm-FT: Full-thickness skin with dermis for wound healing and aging studies
- EpiOcular: Reconstructed cornea-like epithelium for eye irritation (OECD TG 492)
- EpiAirway: Human airway epithelium for respiratory toxicity and infection
- EpiIntestinal: Small intestine model for drug absorption and permeability
REGULATORY VALIDATION
- OECD TG 431: EpiDerm validated for skin corrosion testing
- OECD TG 439: EpiDerm validated for skin irritation testing
- OECD TG 492: EpiOcular validated for eye irritation assessment
- EPA/FDA: Accepted for chemical and pharmaceutical safety submissions
MARKET LEADERSHIP
MatTek models are used by major cosmetics companies (L'Oréal, P&G, Unilever), pharmaceutical firms, and chemical manufacturers globally. The company's consistent quality and regulatory acceptance have made EpiDerm the gold standard for in vitro dermal testing.