COMPANY OVERVIEW
BioIVT, headquartered in Westbury, New York, is a leading provider of human and animal biological products for drug discovery and development. The company supplies primary hepatocytes, liver subcellular fractions, plasma, serum, and tissue matrices that enable pharmaceutical ADME-Tox studies, supporting thousands of drug development programs globally.
PRODUCT PORTFOLIO
- Primary Hepatocytes: Cryopreserved human hepatocytes with characterized CYP450 activity
- Liver Fractions: Microsomes, S9, cytosol for metabolic stability and DDI studies
- Hepatocyte Media: Optimized culture systems for extended function
- Plasma & Serum: Normal and disease-state samples for biomarker research
- Tissue Matrices: Fresh and frozen tissues for PK and distribution studies
KEY APPLICATIONS
- Metabolic stability assessment and metabolite identification
- CYP450 inhibition and induction studies for DDI prediction
- Transporter phenotyping and drug uptake/efflux studies
- Hepatotoxicity screening with primary human hepatocytes
- Biomarker discovery using characterized patient samples
QUALITY & COMPLIANCE
BioIVT maintains rigorous quality systems with full donor traceability, IRB compliance, and consistent product characterization. Their hepatocyte lots are extensively tested for viability, plating efficiency, and metabolic function, ensuring reproducible data for regulatory submissions.