Live News Categories
ORGAN-ON-CHIP
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Engineered Chitosan Nanoparticle Platform Enables Controlled Ibuprofen Delivery and Coordinated Neuroimmune Regulation in a Human Microphysiological Model
Ascending infection of Gardnerella spp. and compartmentalized inflammatory response in fetal-maternal interface organ-on-chip model
Decoding microplastic toxicity on human health: navigating translational challenges using organ-on-chip models
EnView: a tunable microphysiological platform with human crypt-scale topography and independent apical-basal flow for long-term culture and imaging of colonic epithelial monolayers
Integrated "gut-liver"-on-a-chip (iGLoC): an immune-competent and metabolically active microphysiological model of the gut-liver axis for drug screening, validated by abemaciclib pharmacokinetics, hepatotoxicity, and drug-drug interaction studies
Zonation Hallmarks in Human PSC-Derived Hepatic Organoids Integrated into an Immune-Compatible Organ-on-Chip for Liver Injury Modeling
Electrochemical impedance spectroscopy supporting live imaging for barrier assessment in a microphysiological system
Chamber-Design-Associated In Situ Formation of HepG2 Spheroids in a Perfusable Organ-on-a-Chip
Sensor-Integrated Organ-on-a-Chip Platforms: Advances in Drug Evaluation and Disease Modeling
Systematic evaluation of deep learning design choices for image-based organ-on-chip quality assessment
Microphysiological models of human gastrointestinal diseases
Engineering human multi-organ tissue chip niches for drug absorption, distribution, metabolism, excretion and toxicity prediction
Real-time integrated and multiplexed electrochemical sensor for reactive oxygen species in a high-throughput microphysiological system
Microphysiological Systems Integrating Bioprinting, Organoids, Organ-on-a-Chip, and AI: Next Generation Platforms for Pharmaceutical Development
Artificial intelligence across Organ-on-a-Chip workflows: current implementations and future approaches
Tumor-on-chip and cancer microphysiological platforms: knowledge structure, thematic evolution, and the emergence of organoid-integrated models, 2010-2025
Bridging the gap: using organ-on-a-chip technology to evaluate nanoparticle enzyme replacement therapy for lysosomal storage diseases
Hydrogels and microfluidics: toward more physiologically relevant organ-on-a-chip models
A human iPSC-derived kidney-liver organ-on-a-chip platform for modeling inter-organ crosstalk
Modeling sympathetic neuro-cardiac interactions in a hiPSC-based microphysiological system
ORGANOIDS
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Acinar-Derived Organoids Reveal Stage-Specific Control of Acinar Plasticity
Molecular Signatures of HIV-Induced Neuroinflammation and Neurodegeneration in Human Cerebral Organoids: Identification of Therapeutic Targets for NeuroHIV
Exposure to Common Endocrine-Disrupting Chemicals May Alter Normal Breast Development
Human iPSC-derived liver organoid model multicellular tissue responses and therapeutic rescue in Wolman disease
TGF-β Inhibition Attenuates Tau Accumulation and Neurodegeneration in Progressive Supranuclear Palsy Patient-Derived Organoids
Modeling Moyamoya disease using patient-derived induced pluripotent stem cells and organoids
Human iPSC-derived lens organoids recapitulate lens development and morphogenesis in vitro
Organoid technology: a new approach to veterinary drug testing
Multi-omic profiling of 85 iPSC lines from familial dementia reveals cellular diversity and regulators of organoid development
Cellular diversity in neural organoids is critical for neurodegenerative disease modeling
Targeting P2Y14R inhibits proliferation of cervical cancer cells and organoids and activates cAMP/PKA/CREB signaling pathway
Stage-specific exposure to an activity-permissive medium enhances neuronal activity in oligodendrocyte-enriched cortical organoids
Patient-derived gastric cancer organoids for functional precision oncology: disease-specific bottlenecks and clinical readiness
Patient-Derived Organoids and the Next Phase of Functional Precision Oncology
Microencapsulated tumor organoids maintain drug sensitivity stratification
Airflow controlled droplet bioprinting enables high-throughput generation of iPSC-derived thymic organoids within vivoT cell functionality
Millifluidic triMEA organoid platform with stretchable microelectrode arrays for parallel organoid electrophysiology under standardized perfusion
SphereChip attaches spheroids and organoids to planar multielectrode arrays with microfluidics
Human Brain Organoids for Studying General Anesthetic Mechanisms: Developmental Vulnerability, Cellular Stress, and Translational Perspectives
A 3D-Printed Biochemical-Mechano-Thermally Responsive Multicellular Tumor Organoid Platform Decodes Biochemical-Physical Regulation of Cancer-Immune Crosstalk and Chemoresistance
DIGITAL TWINS
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Q-LCAN: Anatomy-Constrained Quantum-Agentic Systems for MRI-Derived Structural Surgical Digital Twins in Uterine Adenomyosis
Digital twins in hospital operations management: a structured review and quantitative content analysis of decision support, workflow engineering and resource allocation
A Biomanufacturing Digital Twin for Consistent N-1 Seed Bioreactor Transfers for Commercial Monoclonal Antibody Production
From static digital articulation to the dynamic (4D) digital virtual patient: an umbrella review of digital occlusal analysis and jaw-motion tracking
Exploratory bone-brain transcriptomic associations and an ODE-based digital-twin framework for fracture healing
Exploring nursing students' communication experiences with artificial intelligence-supported virtual patients: a qualitative study
Digital twins in toxicology: Toward predictive, personalized and real-time risk assessment
Digital twin validation and predictive value of delta radiomics based on tabular transformer for synergistic muscle imbalance in lumbar disc degeneration
Agent-based simulation and digital twins in heart failure care: Current evidence, validation and implementation barriers
Graph neural network for predicting reentrant drivers in atrial digital twins
Data, Process, and Data-Driven Representations of Digital Twins in Diabetes: Scoping Review
Retrieval-Augmented Simulation for Interpreting Probabilistic Digital Twins in Type 1 Diabetes
Quantum-Inspired Graph Neural Digital Twins for the sub-microsecond topological co-design and temporal degradation modeling of cellulose, hemicellulose, and lignin smart gels
Self-adaptive nanophotonic metasurfaces enabling digital twins: toward continuous personalized healthcare in aging and disability
Digital Twin-Assisted Risk Disclosure in Adults Undergoing Elective Bronchoscopy: Multicenter Randomized Controlled Trial
Using Digital Twins to Predict Recovery and Decline in Neurological Disorders
Enabling remote rehabilitation through human digital twins: A technological perspective
AI-Powered Virtual Patients in Health Professions Education: Learner Engagement and Knowledge Application
Voice-Enabled Virtual Patients for Interactive Training in Standardized Clinical Assessment: Mixed Methods Pilot Study
General versus site specific quantile random forest models for virtual patient-specific quality assurance of VMAT plans
AI & MACHINE LEARNING
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13 AI drug discovery companies you should know about
A Deep Learning Framework for Accurate lncRNA-Protein Interaction Prediction via Multi-Kernel Graph Embeddings and Self-Attention
Clinical significance of intraoperative dissection time and machine learning-based prediction in laparoscopic distal gastrectomy for gastric cancer
Keeping artificial intelligence agents within the clinical task
Molecular characteristics and formation mechanisms of chlorinated disinfection byproducts from diatomaceous organic matter: Deciphering intracellular vs. extracellular contributions via FT-ICR MS and machine learning
The missing layer: decision integrity as a verifiable assurance layer in interpretive clinical artificial intelligence
Interpretable machine learning analysis of immune-inflammatory biomarkers for predicting no-reflow in patients with acute myocardial infarction after percutaneous coronary intervention
Deep learning reconstruction in prostate MRI: technical principles, clinical applications, and future directions
Automated Segmentation of Wound Bed Tissue from Clinical Photographs: A Benchmark of Five Deep Learning Architectures Under a Shared Protocol
Machine Learning in Hand Pathology Diagnosis: A Narrative Review of Current Insights
Non-invasive diagnosis of endometriosis: From expert imaging to molecular and artificial intelligence-enabled pathways
Establishing Diagnosis Models for Autism Spectrum Disorder With Auditory Brainstem Response Using Machine Learning Methods
AI Biotech Iambic Gets $150M in IPO Cash for ‘Molecular Superintelligence’ Drug R&D
Advancing Cancer Biomarker Discovery Through Multi-Omics, Bioinformatics, and Artificial Intelligence: A Systematic Review
From discrimination to transportability: Interpreting machine-learning prediction of antitubercular drug-induced liver injury
Navigating the Regulatory Landscape of Artificial Intelligence in Australian Clinical Dentistry
Artificial intelligence in sepsis care and research: aligning clinical questions with model selection and human oversight
Machine Learning Models Combining [68Ga]Ga-PSMA-11 PET Radiomics and Clinical Features to Predict Overall Survival for Metastatic Castration-resistant Prostate Cancer Treated with [177Lu]Lu-PSMA Radioligand Therapy
‘We’ve been taking our time’: Buzzy AI biotech Xaira reveals antibody platform, first taste of pipeline
‘A plate of spaghetti’: Talus Bio boasts 5,000-fold faster drug screening by skipping protein folding
CLINICAL TRIALS
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Author Correction: FcRH5×CD3 bispecific antibody cevostamab in relapsed or refractory multiple myeloma: a phase 1 trial
Cyrano’s Phase II trial of CYR-064 meets primary safety endpoint
RESULT-Hip. The impact of restrictive compared with liberal transfusion strategy on cardiac injury and death in patients undergoing surgery for hip fracture : protocol for a multicentre, randomized controlled trial of two blood transfusion strategies
Lateral Opening-Wedge Versus Medial Closing-Wedge Distal Femoral Osteotomy for Adolescent Idiopathic Genu Valgum: A Randomised Controlled Trial
Effectiveness of a Humor-Integrated Cognitive-Behavioral Psychoeducation Program for Depression: A Randomized Controlled Trial
Early Time Course of Symptom Improvement With Remibrutinib in Chronic Spontaneous Urticaria: Pooled Post Hoc Analyses of the REMIX-1/2 Phase 3 Studies
A randomized controlled trial of a novel AI-based prognostic decision support tool integrated into the electronic health record for ischemic heart disease: Rationale and design of the PM Heart trial
Targeting affective cognition during pregnancy to prevent postpartum depression: a randomized controlled trial with parity-specific effects
Acute Otitis Externa-Antimicrobial Resistance in the US and Canada: Phase III Study Outcomes
Final analysis results from DREAMM-3, a phase 3 study of belantamab mafodotin versus pomalidomide plus dexamethasone in patients with relapsed/refractory multiple myeloma
Efficacy and safety of litifilimab in cutaneous lupus erythematosus: 24-week results of the randomized phase 2 study, AMETHYST
Phase 2 study of fazpilodemab, a FGFR1/Klothoβ agonist, in metabolic dysfunction-associated steatohepatitis (MASH)
Multidimensional Clinical Benefits of Cinnamon Leaf Oil Inhalation in Primary and Metastatic Brain Tumor Patients During Winter: A Randomized Controlled Trial
Embodied Inter-Hand Sensory Experiences ("Prana" Perception): A Randomized Controlled Trial of Affective, Environmental, and Physiological Correlates
Daily Caloric Restriction in Overweight and Obese Adults with ADPKD: Rationale and Protocol of a Randomized Controlled Trial
First patient dosed in MacroGenics’ Phase I MGC030 trial
Experimental Cataract Lens Can Treat Glaucoma Through Time-Release Drugs
Carbon nanoparticle-Fe (II) complex for ferroptosis therapy in refractory solid tumors: a phase I trial
Systemic and Mucosal Antibody Responses Against Neisseria gonorrhoeae (Ng) Outer Membrane Vesicle Antigens following Four-Component Meningococcal Serogroup B (4CMenB) Immunization in Healthy Adults: A Randomized Phase II Trial
Response to the letter to the editor- phase III trials in retinal biosimilars: parity before pragmatism
REGULATORY
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Comparative Evaluation of Power-Law and Viscoelastic Hemolysis Models in the FDA Nozzle Benchmark Geometry
Malfunction Reporting Patterns in Life-Supporting Versus Noninvasive Ventilators: A Stratified Text-Mining Analysis of the FDA Device MAUDE Database
FDA Approves a Second Weekly Basal Insulin Option for Type 2 Diabetes
FDA Policy Changes on Stability Studies for PET Drugs Manufactured Within Networks
Perspectives on FDA Guidance for Myelodysplastic Syndromes
Evaluation of the accuracy, completeness, and compliance of current summary reporting of adverse events to the Food and Drug Administration using the manufacturer and user facility device experience (MAUDE) database: cross sectional study
Review of embryo-fetal developmental toxicity studies performed for pharmaceuticals approved by FDA in 2024 and 2025
Happy Health’s Cuffless BP Device Wins FDA Clearance
Disproportionality Analysis of Reporting Signals for Pericardial Disorders in the FDA Adverse Event Reporting System, 2000 to 2025
Manufacturing Quality Issues in Healthcare and Cosmetics: An Analysis of FDA Surveillance Data
Audiovestibular adverse event reporting profiles of GLP-1 receptor agonists: A case-case pharmacovigilance study using FDA AEMS data
Performance evaluation of antimicrobial susceptibility testing devices across CLSI, EUCAST, ISO, FDA, and EMA frameworks: implications for breakpoint application
Adverse event reporting of golimumab: A disproportionality analysis of the FDA Adverse Event Reporting System (FAERS) database
Nanoparticles and Medicine Thirty Years After the First FDA Approval: Time to Renew the Vows
Early Uptake of Oral Semaglutide for Obesity Treatment After Regulatory Approval
The Legal Battle Over Mifepristone and the Future of FDA Regulation
Asahi Kasei Acquisition Pays Off With FDA Approval for Novel Herpes Drug
Abbott nabs FDA approval for new CardioMEMS HF System that allows heart readings to be seen at home
Trump's FDA pick Heidi Overton calls vaccines, mifepristone safe and effective in confirmation hearing
Elevar wins FDA nod for bile duct cancer drug Lyrfigtu, a first for a Korean firm
DRUG DISCOVERY
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13 AI drug discovery companies you should know about
Context-dependent immunomodulation by Astragalus polysaccharides: Structural determinants, structure-activity relationships, mechanisms, and applications: A review
Computer-aided development of novel thiazolidinone-thiazole derivatives: multidimensional structure-activity relationships revealed by quantum chemical analysis, molecular docking and biological investigation
HDAC8 Assistant: a QSAR-guided molecular generation platform for de novo design and virtual screening of HDAC8 inhibitors
Targeting fibroimmune remodeling in androgenetic alopecia: emerging opportunities for RNA-based drug discovery
Large Language Model-Assisted Prediction and Virtual Screening of Near-Infrared-II Fluorescent Molecules
Structure-activity relationship of Cu(II) and Pd(II) thiosemicarbazone complexes with anticancer and antibacterial properties
Toxoplasmosis: Epidemiological Significance, Economic Burden, and Emerging Directions in Drug Discovery and Artificial Intelligence
Current applications of isothermal titration calorimetry for lead optimization
A practical guide to atropisomerism: fundamentals and case studies from modern drug discovery
Concept Life Sciences appoints Dr Adrijana Vinter as Chief Executive Officer
Unveiling Structure-Activity Relationship With Structurally Defined and Stabilized Cu-Based Molecular Hybrid Electrocatalysts in CO2 Electroreduction
Antiproliferative activities of panduratin A and its derivatives against U-251 MG glioblastoma cells and U-251 MG cancer stem-like cells: structure-activity relationships and identification of PHB2 as a candidate binding protein
From artificial intelligence promise to translational practice in drug discovery: Reproducibility, validation and evidence-based implementation
Sacha Inchi (Plukenetia volubilis L.) polysaccharides and related carbohydrate products: Extraction, structural diversity, bioactivities, structure-activity relationships, and sustainable valorization
Proteome-guided drug discovery maps and mitigates therapeutic degrader toxicity
ELRIG and The Protein Society announce keynote speakers for Protein Sciences in Drug Discovery 2026
Carterra advances lab-in-the-loop drug discovery through new scientific collaboration
Evaluating generative models for structure-based drug discovery from de novo design to lead optimization
‘A plate of spaghetti’: Talus Bio boasts 5,000-fold faster drug screening by skipping protein folding
INDUSTRY
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From strategy to scale: How Saudi Arabia is building a biotech ecosystem
Iambic CEO on taking an AI drug company public
OrbiMed raises $3bn to back global life science players
Acta Pharmaceuticals raises $24m for Alzheimer’s therapies
AI Biotech Iambic Gets $150M in IPO Cash for ‘Molecular Superintelligence’ Drug R&D
Preclinical Pulse: The research catching our eye in October 2026
Pushing biotech forward in France: 10 companies to know about
Saudi Arabia's biotech momentum: inside RGMBS 2026
From strong science to mature companies: The next test for Spanish biotech
Top biotech deals in September 2026
ArriVent’s phase 3 lung cancer trial flops, sinking stock
Forbion’s ‘landmark’ €2.3B fundraise to benefit 30 ‘high potential’ biotechs
AstraZeneca hopes to ‘achieve amazing things’ with new Kendall Square R&D center
TRex Bio stomps toward $111M IPO, as Retension and Lycia also gear up to go public
Biotech’s peptide shows promise as ‘bait molecule’ to treat neuropathic pain in mice
Vaxcyte’s stock jumps as pneumococcal vaccine holds its own against Pfizer's, Merck’s shots
Gate CEO sees expanded $870M pact with Lilly as ‘vote of confidence’ in biotech’s platform
‘We’ve been taking our time’: Buzzy AI biotech Xaira reveals antibody platform, first taste of pipeline
Immunotherapy startup Adecto blames ‘risk-averse funding environment’ for closing down
There Is No Such Thing as a Typical Biotech
RESEARCH
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Scientists discover immune pathway behind radiation-induced lung damage
Scientists finally uncover why statins can cause muscle pain
Scientists discover a surprising link between vitamin C and cancer survival
Why painful arthritis can return stronger after cancer treatment
Just 3,000 steps a day may help slow Alzheimer's, scientists find
Fatty liver disease is actually five different conditions, scientists discover
Magic mushroom ingredient takes the fight out of aggressive fish
Scientists discover that male and female skin play by different rules
Scientists discover how deep sleep builds muscle, burns fat, and boosts the brain
Scientists discover how exercise reverses muscle aging
Scientists discover a surprising danger in smaller cancer cells
Scientists find a surprising genetic twist behind octopus intelligence
Scientists find hidden driver of aging and a simple amino acid that fights memory loss in mice
Scientists discover 5 hidden brain patterns behind depression
A new way to fight gum disease without wiping out good bacteria
Scientists discover cells that cheat death and rebuild damaged tissue
Hidden “immune organ” in the skull may help fight brain cancer
Scientists find how “zombie” cells fuel inflammation as we age
Scientists discover the human heart can regrow muscle after a heart attack
Scientists find the “Achilles’ heel” of deadly gut bacteria
TECHNOLOGY
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Precise detection of telomerase reverse transcriptase C228T mutation using label-free and magnetically induced self-assembly electrochemical biosensors
Diffusion-Limited Microfluidic Focusing: Oscillatory Electro-Viscoelastic Migration of Nanoparticles and Extracellular Vesicles
Advances in influenza A and B virus detection: molecular diagnostics, biosensors, and point-of-care applications
Detection of unamplified mycobacterium tuberculosis genomic DNA in sputum samples using a metal-enhanced fluorescence-based biosensor
Recent developments of fluorescent proteins and biosensors driven by cross-disciplinary insights
Prediction residuals in spatial transcriptomics reveal microenvironmental heterogeneity in cancer
Dielectrophoresis-Assisted PVDF/DES/Au NP-Based Microfluidic ECL Biosensor for In Situ Detection of Extracellular Vesicles
High-Throughput Screening of a Lipid Nanoparticle (LNP) Library Identifies Lead Formulations for CRISPR-Cas9 Ribonucleoprotein Delivery and Gene Editing
Astaxanthin-zein-polysaccharide nanoparticles via intelligent microfluidics: Ionic-type polysaccharides differentially regulate stability and intestinal sustained release
Rapid and visual detection of group B Streptococcus based on an ERA-CasMNPs colorimetric biosensor
Spatial transcriptomics unveils the in situ cellular and molecular hallmarks of the lung in fatal COVID-19
Deep Learning and Domain Expertise for Fabricating High-Performance Biosensors
Optical biosensors for cancer diagnosis and monitoring
Raman-Grounded Deep Learning for Calcium Carbonate Polymorph Sensing during Microfluidic Biomineralization
Comparative investigation of extended-gate GaAsSb/InGaAs HTFET biosensors for label-free biomolecule detection
Microfluidic Focusing of Heterogeneous Bacterial Immunocomplexes for Reproducible SERS Immunoassays
Integrated Viscoelastic Microfluidics for Label-Free Separation and Concentration of Circulating Tumor Cells
Biomarkers, Biosensors, and Wearables: Overview of Current Uses in Medicine and Challenges for Application to Mental Health
Biochar-based biosensors: from sustainable carbon materials to next-generation sensing platforms
Automated sample preparation microfluidic platform for immuno-LAMP detection: application to troponin I quantification
CRISPR & GENE EDITING
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Genome-wide CRISPR screen identifies mutation-specific pathways converging on TAZ/TEAD activation in mutant p53-driven breast cancer
Development of a Rapid RPA-CRISPR/Cas12b Assay for Dual Detection of Hantaan Virus and Seoul Virus
Protocol for eVLP-mediated CRISPR-Cas9 and prime editing in pancreatic cancer cell lines
Utilization of the CRISPR-Cas system for investigating tuberculosis drug resistance
Structural basis for loop-dependent inhibition by AcrIIC1 anti-CRISPR proteins
CRISPR screens identify ACSL4 as a key regulator in macrophage activation and metabolic inflammation
The CRISPR-dCas9 epigenetic toolbox: prospects for modulating gene expression in climate-resilient crops
Development and Evaluation of an RPA-CRISPR/Cas12a Molecular Assay for Rapid Diagnosis of Theileria annulata Infection in Bovines
Programmable and selective silencing of oncogenic fusion transcripts by CRISPR-Cas13b via breakpoint sequence recognition
Chemogenetic ubiquitin E1 inhibitor TAK-243 CRISPR screen uncovers HAPSTR1/HUWE1 axis in chromatin proteostasis and cell cycle control
Precision gene editing in infant neuroblastoma: a review of nanoparticle: enabled CRISPR/Cas9 therapies
Author Correction: UNCOVERseq enables sensitive and controlled gene editing off-target nomination across CRISPR-Cas modalities and systems
A cryptic binding pocket regulates the metal-dependent activity of Cas9
Manipulating rRNA levels with CRISPR
Correction: CRISPR/Cas9-mediated gene correction of Wilson disease H1069Q point mutation in patient-specific induced pluripotent stem cells
Site-specific RNA photocrosslinking of CRISPR-associated and viral RNA-binding proteins using genetic code expansion
Bigger than CRISPR? A guide to the latest genome editors
CRISPR-based gene drive systems alter the transcriptome in Anopheles gambiae mosquitoes
CRISPR could help doctors attack blood cancer without destroying healthy cells
Author Correction: Tracking-seq: a universal off-target detection approach for CRISPR–Cas genome editing
CELL & GENE THERAPY
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CAR-T Cell Therapy in Solid Tumors: Implications of Satri-cel for Gastric and Gastrointestinal Cancers
Designing the Ecosystem for CGT Success
The allogeneic eDN70(-) CAR-T Cells Without TCR or MHC Editing Exhibit Enhanced Persistence and Function
CAR-T-centered sequential therapy: current status, challenges, and future clinical perspectives
Persistent CAR-T donor cells contribute to mixed chimerism with cytopenia after CAR-T-bridged allo-HSCT: rescue by CAR-target-knockout DLI in three cases
A reality check for autoimmune CAR T cells
NKG2D overexpression potentiates CAR-T cells through costimulation by tumor NKG2D ligands
Synthetic Notch CD123 and CLL1 chimeric antigen receptor T-cells (CAR-T) target acute myeloid leukemia and reduce off-tumor effects associated with CLL1 CAR-T cells
Chimeric Antigen Receptor T-Cell Therapy in T Cell/Histiocyte-Rich Large B-Cell Lymphoma: A Systematic Review and Meta-Analysis
Next-generation natural killer cell therapy: bench to bedside and beyond
Outcomes of ibrutinib plus lenalidomide combination in patients with large Bcell lymphoma refractory to or relapsing after CAR-T-cell therapy and who failed or were ineligible for bispecific antibodies: a multicenter real-world REALI-T study
CAR T-cell activity for autoimmune diseases across EBMT centers: an international survey on behalf of the Autoimmune Diseases Working Party and the Cellular Therapy and Immunobiology Working Party
Transformation to Plasmablastic Lymphoma Following CD19-Directed CAR T Cell Therapy for Refractory Diffuse Large B Cell Lymphoma: A Case Report
CAR T cells from code to clinic: Framing modeling approaches with current translational research goals
Emerging immunotherapies in melanoma beyond immune checkpoint inhibitors: Vaccines, intralesional therapies, adoptive cell therapies, and T-cell engagers
Scientists reprogram immune cells inside the body to fight cancer
Novartis pens $7.8B deal for Abogen's in vivo autoimmune T-cell engager
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases
Author Correction: Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells
Cellares pens 2nd automation test with Asia-based cell therapy partner in 2 weeks
BIOPRINTING
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A multi-component polymeric bioink formulation developed using an in-house integrated bioextruder
3D-bioprinted dual-factor nerve conduits promote neurovascular co-regeneration via activation of the PI3K/AKT and MAPK/ERK pathways
Emerging Strategies for Bioprinting Organized Musculoskeletal Tissues with Biomimetic Collagen Architecture
Airflow controlled droplet bioprinting enables high-throughput generation of iPSC-derived thymic organoids within vivoT cell functionality
Next-generation hydrogels and strategies to recreate 3D tumour microenvironments for osteosarcoma: from bioprinting to therapeutic testing
3D bioprinting and scaffold technology applications for the management of lung diseases
3D bioprinted porous PLLA implants with dual gene modified BMSCs for osteoarthritis cartilage repair
Cell-Laden 3D-Bioprinted Artificial Skin Grafts for Tissue Engineering Wound Healing
MLATE V3: An Open-Source Multi-Tissue AI Framework for Data-Driven Optimization of 3D-Printed and Bioprinted Scaffolds
3D bioprinting in dermatological therapeutics: Technologies, applications, and clinical perspectives
Spatially Controlled Release from Printable Microgels for Embedded Bioprinting
DLP Bioprinting of Bilayer Recombinant Collagen Scaffolds for Immunoangiogenic Microenvironment Remodeling and Diabetic Wound Regeneration
3D Bioprinted Blood-Brain-Tumor Barrier Spheroid-Based In Situ Evaluation of Anticancer Compounds Against Glioblastoma: ROS-Producing Ruthenium as a Potential Therapeutic Candidate
Microenvironment-Driven 3-Dimensional Biofabrication Enables Sequential Maturation of the Blood-Brain Barrier
Perspectives on the future of biofabrication: insights from the winter school for biofabrication
Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening
Engineering neurovascular thrombosis: Light-based bioprinting for patient-specific modeling and women's cerebrovascular health
Proof-of-concept validation and characterisation of a DLP 3D bioprinted vascularised colorectal cancer model
A Reproducible MRI-Based Pipeline for Longitudinal Tracking of Laser-Assisted Bioprinted Cells in Three-Dimensional Constructs
Bioprinting of BSA membranes with C2C12 and NIH 3T3 pre-cellularized PLGA microscaffold: a step toward diaphragmatic hernia patches
PRECISION MEDICINE
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From Paracelsus to Precision Medicine: Paediatric Epilepsy as the Paradigm of Individualized Therapy
Utility of pharmacogenomic tests in treating pediatric depression, anxiety and ADHD
Quantifying the diagnostic time gap in precision oncology: A retrospective analysis of potential time savings from same-day cartridge-based molecular testing versus next-generation sequencing in cytology specimens
Fluorogenic RNA aptamers in cancer: emerging platforms for molecular imaging, biosensing, and precision oncology
When Actionable Genomic Findings Do Not Translate into Treatment in Precision Oncology
Navigating the landscape of targeted therapies for renal cell carcinoma in the era of precision medicine (Review)
Evolution of Targeted Temperature Management Duration: From a One-Size-Fits-All Approach to Precision Medicine
Precision Medicine in Sickle Cell Disease: From Molecular Pathways to Curative Strategies
From early recognition to precision medicine: advances in the diagnosis and management of adult sepsis and septic shock-a narrative review
An imprecise label in the era of precision medicine: labelling and access for daraxonrasib, the first pan-RAS inhibitor approval
The maturation of precision medicine into pragmatic, patient-centered care: A commentary on the 2026 EHA CLL Guidelines
An imprecise label in the era of precision medicine: labelling and access for daraxonrasib, the first pan-RAS inhibitor approval
Cancer plasticity and histological transformation as adaptive resistance mechanisms in precision oncology
Patient-derived gastric cancer organoids for functional precision oncology: disease-specific bottlenecks and clinical readiness
Patient-Derived Organoids and the Next Phase of Functional Precision Oncology
MicroRNAs and Precision Medicine in Acute Respiratory Distress Syndrome: Moving beyond Clinical Phenotypes
CardioPharmaGENET: a new European network for pharmacogenomics-driven cardiovascular care
Consistency of Serial Cerebrospinal Fluid α-Synuclein Seed Amplification Assay Results in the Parkinson's Precision Medicine Initiative
Ageing, women's health and personalised medicine: Advancing artificial intelligence and therapeutics through the blueprint theory paradigm
Bridging the pharmacogenomics gap: a survey of healthcare workers in South-Western Nigeria
STEM CELLS
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Chemical reprogramming of human pluripotent stem cells into 8-cell-like states
The prognostic impact of CEBPA mutation in acute myeloid leukemia patients undergoing allogeneic hematopoietic stem cell transplantation
Ketamine induces synaptic and monoaminergic remodeling in human iPSC-derived neurons
Human iPSC-derived liver organoid model multicellular tissue responses and therapeutic rescue in Wolman disease
IL-12-producing iPSC-derived antigen-presenting cells enhance antitumor immunity and enable off-the-shelf immunotherapy
AI-integrated iPSC multi-omics: advancing phenotype discovery and drug target identification in rare diseases
Modeling Moyamoya disease using patient-derived induced pluripotent stem cells and organoids
iPSC neurodegenerative disease initiative isogenic CAG repeat iPSC line for Huntington's disease
Identification of cellular double-stranded RNAs in mammalian embryonic stem cells
Human iPSC-derived lens organoids recapitulate lens development and morphogenesis in vitro
Female iPSC X chromosome inactivation erosion and its transcriptomic effects during CRISPR gene editing and neural differentiation
Programming brain endothelial identity: Transcription factor and genome engineering approaches to improve iPSC-derived BBB models
Donor-intrinsic regenerative potential outweighs histocompatibility in iPSC-derived skeletal muscle engraftment in nonhuman primates
Gaps in guidelines implementation and need for harmonization in toxoplasmosis management after allogeneic stem cell transplantation across EBMT centers: an Infectious Diseases Working Party survey
Inhibition of endogenous TGF-β normalizes extracellular matrix deposition in hiPSC-derived fibroblasts
Priming of human iPSCs with doxorubicin causes genome-wide transcriptional reprogramming and functional impairments in iPSC-derived cardiomyocytes
New signaling pathway enhances blood stem cell transplantation outcomes
Correction: CRISPR/Cas9-mediated gene correction of Wilson disease H1069Q point mutation in patient-specific induced pluripotent stem cells
Correction: Secondary autoimmune and inflammatory diseases after allogeneic hematopoietic stem cell transplantation: a retrospective study from the EBMT transplant complications and autoimmune diseases working parties
Stem cells reverse stroke damage and restore movement in mice
NEW APPROACH METHODS
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Evaluating the biological effects of caffeine-related compounds methylliberine and theacrine by integrated in silico and in vitro new approach methods (NAMs)
New approach methodologies in nanomedicine: bridging the gap between in silico, in vitro, and in vivo systems
In vitro methods for measuring cytotoxic activity of cylindrospermopsin as alternatives to animal testing
Animal Models for Interventional Oncology Research: Overview and Considerations in the Era of New Approach Methodologies
An overview of In vitro genotoxicity testing strategies for fragrance materials: Addressing false positives and advancing non-animal approaches
New approach methodologies to model the female reproductive tract: advances and opportunities for nanomedicine
Advancing component-based mixture risk assessment using new approach methodologies: An environmental case study
Pediatric Developmental Safety Assessment and New Approach Methodologies: US FDA/Triangle CERSI Workshop Report
New approach methodologies in pharmaceutical development: Survey insights on adoption, infrastructure, and the path to broader implementation
Quinoa and Peanut Extracts as Alternatives to Animal-Derived Extracellular Matrix Proteins in Cultured Meat Production
Editorial: Shaping the future of predictive toxicology: addressing challenges and new approach methodologies
Engineering 3D neural models of neurodegeneration: the Neural Microenvironment Design Code (NMDC), design principles, and emerging new approach methodologies
New approach methodologies for in vitro detection of chemical-induced cholestatic liver injury
Human placental transfer of xenobiotics in health and disease: New approach methodologies for developmental and reproductive toxicology testing and mathematical modelling
AI-integrated human-relevant alternatives to animal experimentation in drug development: Toward a predictive translational ecosystem, from in vitro and in silico models to clinical and real-world evidence
New approach methodologies: drug screening platform to identify antifibrotic compounds
Strategic application of New Approach Methodologies (NAMs) in fragrance ingredient safety assessment: Integration of in vitro, in silico, and exposure-based approaches in RIFM evaluations
Harnessing Yarrowia lipolytica as a platform for animal-free and secretory production of human lactoferrin
Editorial: Advancing in vitro cell culture practices: achieving truly animal-free experiments and scientifically reliable and reproducible methods
FUNDING & VC
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Merck KGaA’s $1.1B Silence Therapeutics Buyout Brings RNA Drug for Rare Blood Cancer
STAT+: China moves to restrict foreign biotech acquisitions
City Therapeutics’ Upsized IPO Raises $200M to Bring RNAi Drugs Beyond the Liver
OrbiMed raises $3bn to back global life science players
Acta Pharmaceuticals raises $24m for Alzheimer’s therapies
RougeTx launches with $58 million series A financing for HHT therapy
Outro Raises $7M To Support Safe Deprescribing
Top biotech deals in September 2026
IMMUNOTHERAPY
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Why painful arthritis can return stronger after cancer treatment
Author Correction: FcRH5×CD3 bispecific antibody cevostamab in relapsed or refractory multiple myeloma: a phase 1 trial
Dose Optimization of Immune Checkpoint Inhibitors: A Policy opportunity to reduce costs and improve access to immunotherapy in the United States
Tumor endothelial cells as vascular immune gatekeepers: reprogramming the vascular-immune interface for cancer immunotherapy
Dual Metabolic Inhibition Via Vanadium-NO Synergistic Nanoplatform Potentiates Cancer Immunotherapy
Therapeutic Peptide-Programmed Liquid-Crystalline Topology Switching for pH-Gated Postoperative Cancer Immunotherapy
AI-driven quantitative assessment of abdominal organs and immunotherapy outcomes across multicenter hepatocellular carcinoma cohorts
Liver-specific amino acid metabolism impacts on efficacy of cancer immunotherapy
Immune checkpoint inhibitor-associated myocarditis: clinical and mechanistic insights
Letter to the Editor: Comment on Ni et al.'s " Long-Term Follow-Up of Checkpoint Inhibitor‑Associated Uveitis Treated with Fluocinolone Acetonide Intravitreal Implant in a Pediatric Patient "
Efficacy and safety of immunotherapy plus chemotherapy in elderly patients with advanced gastric cancer: a retrospective study
Immune Profiles and Immunotherapy Efficacy in Sinonasal Malignancies: A Scoping Review
Clinical, Radiologic, and Highest-Grade Assessment of Immune Checkpoint Inhibitor Pneumonitis in Non-Small Cell Lung Cancer
A lectin-directed antibody-recruiting molecule against Tn antigen for cancer immunotherapy
CSHL researchers find way to make immunotherapy effective against colorectal cancer
In vivo engineering of CAR natural killer cells for immunotherapy using ligand-directed lipid nanoparticles
Bowel cancer “melted away” after immunotherapy, then stayed away
Cancer-fighting t cells burn out. Scientists may have found a fix
Genmab’s latest phase 2 data spur claim ADC is ‘clearly superior’ to AbbVie’s Elahere
Immunotherapy startup Adecto blames ‘risk-averse funding environment’ for closing down
MICROBIOME
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Disentangling microbiota-dependent and -independent impacts of antibiotics on host physiology
Targeting the Gut Microbiota-Metabolism Axis: Novel Pharmacological Mechanisms and Translational Application Strategies for Oral Antidiabetic Drugs
The "living well with lupus" lifestyle intervention: Effects on gut microbiota in patients with systemic lupus erythematosus and high cardiovascular risk
Adult-Onset Vitamin-A Deficiency Reshapes the Gut Microbiome and is associated with Sex-Specific and shared Systemic Effects in Adult Wistar Rats
Nifedipine-modulated gut microbiota attenuates hypertensive vascular injury through Bifidobacterium-associated inosine-Adora2b signaling
Poria cocos triterpenes alleviate diabetes mellitus by regulating the gut microbiota-barrier-inflammation axis and inhibiting the TLR4/nF-κB/NLRP3 pathway
Potential Microbiota-Immune-Neural Axis Mechanisms in Orthopedic Chronic Post-Surgical Pain
Exploring gut microbiome dysbiosis in vasculitis in adults: a systematic review
Publisher Correction: Microbiota-derived 10-hydroxystearic acid activates PPARα to restore gut epithelial barrier integrity and enhance anti-retroviral therapy
Habitual Diet, Gut Microbiome Dysbiosis, and α-Synucleinopathy Conversion in Isolated Rapid Eye Movement (REM) Sleep Behavior Disorder
Incidence and Risk Factors for C. difficile Reinfection After Faecal Microbiota Transplantation or Antibiotic Therapy
Intratumoral microbiota in cancer immunotherapy: metabolic-epigenetic crosstalk and engineered bacterial therapeutics
Publisher Correction: Microbiota-derived 10-hydroxystearic acid activates PPARα to restore gut epithelial barrier integrity and enhance anti-retroviral therapy
Microbiome Targeted Therapies for Primary Sclerosing Cholangitis
Schinifoline attenuates atherosclerosis and modulates gut microbiota and bile acid metabolism in ApoE-/- mice
Fecal Microbiota Transfer for Recurrent Clostridioides difficile Infection: A Retrospective Single-Center Analysis
A high-resolution spatial model of the primate gut microbiome defines niche-specific functions and host-adapted microbial metabolism
Discovering gut microbiome signatures that predict adverse and reverse cardiac remodeling in preclinical heart failure
Genome mining of the tumor microbiome reveals biosynthetic diversity and potential pathology-modulating metabolites
Sugar-rich foods exacerbate antibiotic-induced microbiome disruption
CARDIOVASCULAR
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Investigating the Role of Tetranectin in Ischaemic Heart Disease and Heart Failure
Sustained improvement in sickle cell cardiomyopathy after haematopoietic stem cell transplantation is superior to that with disease-modifying therapy
LUR1 (SPRING1) promotes sortilin-induced macrophage lipid accumulation and aortic atherosclerosis via furin maturation
Menstrual Health in Children, Adolescents, and Young Adults with Cardiac Disease: An Underrecognized Component of Heart Failure, Mechanical Circulatory Support, and Transplant Care
Tryptophan Metabolism in Heart Failure: Mechanisms, Biomarker Potential, and Therapeutic Implications
GLP-1 receptor agonist therapy and incident atrial fibrillation in non-diabetic adults with obesity and chronic kidney disease: a propensity matched cohort study
CA125 and the right ventricle in acute heart failure: A marker of dysfunction or congestion?
Changing global prevalence of diuretic resistance amongst patients with heart failure: a systematic review and cumulative meta-analyses
Complement C3a plays a role in diabetic cardiomyopathy mainly via C3aR-ERK-PANoptosis pathway
Periodontal Disease and Heart Failure: Current Evidence and Perspectives
A Transcritical Bifurcation at Infinity Governs Plaque Stability in a Lipid-Structured Macrophage Model of Atherosclerosis
Prognostic Impact of Moderate Secondary Mitral Regurgitation After Optimized Medical Therapy in Heart Failure
Beyond the Gradient: Patient-Reported Outcomes with Aficamten in Obstructive Hypertrophic Cardiomyopathy
High Lipoprotein(a) Is a Predictor of Adverse Events and Heart Failure in Patients With Acute Myocardial Infarction
Validation of an Electronic Health Record Model for Unplanned Readmission in Patients With Heart Failure
Sacubitril/Valsartan Improves Cardiovascular Outcomes in Elderly Patients with Coronary Artery Disease and Hypertension: A Retrospective Cohort Study
Perioperative Management of a Toddler With Tuberous Sclerosis and Dilated Cardiomyopathy Undergoing Open Abdominal Aortic Aneurysm Repair: A Case Report
Drug-Drug Interactions vs. Therapeutic Combinations in Patients with Congestive Heart Failure and Diabetes: An Ambispective Real-World Study
Before the crisis: a call for nurses to lead crucial conversations in heart failure care
Long-term outcomes and impact of diagnostic coding of patients with heart failure identified in primary care: insights from the OSCAR-HF cohort
ONCOLOGY
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Why painful arthritis can return stronger after cancer treatment
Tumor and ctDNA concordance of actionable alterations in metastatic breast cancer
Surgical Treatment of Tumor-Induced Osteomalacia With Causative Tumors Affecting the Long Bones
Neuro-Immune Interactions in the Tumour Microenvironment: Implications for Cancer Progression and Treatment
Multifunctional Magneto‑Thermal Probe Enhances the Efficacy of Tumor Therapy as a Tumor Nanovaccine
DNA Nanostructures for Overcoming Cancer Drug Resistance: Mechanisms, Therapeutic Strategies, and Translational Challenges
An Integrated Approach to MSI-High Colorectal Cancer Therapy in a Young Patient: A Clinical Case
CYB5R1 drives stemness and malignant progression via STAM2/STAT3 in chemotherapy-enriched triple-negative breast cancer
Multi-omics liquid biopsy for leptomeningeal metastases in lung cancer: from molecular mechanisms to precision diagnosis and treatment
Editorial Comment: Rethinking Local Control in Stage IV EGFR-Mutant NSCLC: A Biologic Rationale for Primary Tumor Resection in the Era of Targeted Therapy
CSHL researchers find way to make immunotherapy effective against colorectal cancer
More options, better odds: the changing prostate cancer treatment landscape
The conformation-selective PI3Kδ inhibitor roginolisib in patients with advanced or metastatic cancer, including metastatic uveal melanoma: first-in-human clinical trial
Scientists just found a way to fight lung cancer and muscle wasting at the same time
Vitamin D drug may help crack pancreatic cancer’s protective shield
Scientists say house cats could help unlock better cancer treatments for humans
A major risk of breast cancer screening may have been overestimated for decades
Elevar wins FDA nod for bile duct cancer drug Lyrfigtu, a first for a Korean firm
This new drug could break cancer’s resistance to treatment
Bayer offloads cancer drug Stivarga to Grünenthal for up to $431M as new competition looms
NEUROSCIENCE
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"Mind-blowing" Alzheimer’s breakthrough: Two hours of sleep restored without clearing brain plaques
Plasma eMTBR-tau243 and p-tau205 as T2 biomarkers for biological staging and prognosis in Alzheimer’s disease
Apolipoprotein E4 and immune dysfunction in Alzheimer's disease: mechanisms and therapeutic implications
Zona incerta circuits in cognition and the regulation of sleep and wakefulness: potential relevance to Alzheimer's disease
A critical mechanistic synthesis of PINK1-mediated mitophagy signaling and its therapeutic targeting in Parkinson's disease neurodegeneration
Mincle exacerbates neuroinflammation and dopaminergic neurodegeneration via synergistic crosstalk with TLR4
AKAP1 Protects Retinal Ganglion Cells and Preserves Vision by Improving Mitochondrial and Synaptic Health in Glaucomatous Neurodegeneration
Molecular Signatures of HIV-Induced Neuroinflammation and Neurodegeneration in Human Cerebral Organoids: Identification of Therapeutic Targets for NeuroHIV
Dysregulated Metal Homeostasis in Alzheimer's Disease: From Pathological Modulators to Therapeutic Targets
Projected burden of cold spell-attributable Parkinson's disease mortality among older adults in China under climate change and population ageing
A multimodal MRI-based study of early-stage Parkinson's disease across age-at-onset groups
A natural neuronal receptor-derived MRI probe targets β-amyloid oligomers for the diagnosis of Alzheimer's disease
Peripheral and cerebrospinal fluid inflammatory markers in sporadic amyotrophic lateral sclerosis an exploratory cross-sectional association study
miR‑660‑5p ameliorates neuronal damage in Alzheimer's disease via targeting APP
Association between IGFBP-3 and longitudinal neuropsychiatric symptom trajectories in early Parkinson's disease: a longitudinal cohort study
Patterns of Stakeholder Participation in Advance Care Planning for Older Adults With Alzheimer's Disease in China: A Cross-Sectional Study
Sublexical compensatory reorganization of Chinese character recognition in Alzheimer's disease
Scientists may have overlooked a hidden Alzheimer's culprit for decades
The hidden math of Alzheimer's could point to new treatments
Genentech pays Alector $100M for preclinical Parkinson’s prospect
INFECTIOUS DISEASE
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High-risk antimicrobial resistance genomic traits in multidrug-resistant Salmonella across China’s food chain: projections to 2050
Association Between Neighbourhood-level Antibiotic Utilization and the Rate of Community-Associated C. difficile (CA-CDI) Infection: An Ecological Study
In silico approach to Helicobacter pylori vaccine design
Production of recombinant human proteins in Komagataella phaffii using a sucrose-utilization-based selection marker without antibiotic resistance
Programmable bacterial vaccine vectors: A Design-Build-Control framework for precision immune engineering
A Chiral Virus-Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy
Diagnostic Complexity of Adult-Onset Still's Disease in the Setting of Nosocomial Infection and Antibiotic Hypersensitivity
Neurotoxicity of Broad-Spectrum Antibiotics in Urinary Tract Infections: Mechanisms and Clinical Implications
Acute Otitis Externa-Antimicrobial Resistance in the US and Canada: Phase III Study Outcomes
Expanding antiviral therapy in chronic hepatitis B: Evidence, uncertainties, and clinical considerations
Quorum sensing and quenching as integrated strategies for antimicrobial resistance mitigation in aquaculture: Applications and future directions
Clinical response rates and adverse events associated with therapeutic tumor vaccines in lymphoma: A systematic review
Timeliness of routine childhood vaccination in the Democratic Republic of the Congo: data from national vaccine surveys in 2021/2022, 2023 and 2024
Effect modification of maternal concentrations of per- and polyfluoroalkyl substances on vaccine effectiveness in children up to 6 years of age: The Japan Environment and Children's Study
Safety and immunogenicity of a BPL-inactivated, whole-virus, universal influenza vaccine: a randomized, double-blinded, double-dummy, placebo-controlled, phase 1 clinical trial
Bioengineering strategies for improving the immunogenicity of mRNA vaccines
160-million-year-old proteins show surprising power against superbugs
AI-guided optimization for thermostable mRNA vaccines
Recoding by N1-methylpseudouridine guides rational mRNA vaccine design
Extended dosing intervals enhance the durability of a self-amplifying mRNA vaccine against pandemic H5N1 influenza: a randomized, observer-blind, dose-finding Phase I study
LIQUID BIOPSY
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Tumor and ctDNA concordance of actionable alterations in metastatic breast cancer
Molecular predictors of minimal residual disease in newly diagnosed multiple myeloma treated with quadruplet therapy
Multi-omics liquid biopsy for leptomeningeal metastases in lung cancer: from molecular mechanisms to precision diagnosis and treatment
Prognostic value of circulating tumor DNA in esophageal and gastric cancer by treatment stage: a systematic review and meta-analysis
Value and research advances of ctDNA in perioperative therapy for non-small cell lung cancer
Profiling circulating tumor DNA for recurrence prediction and prevention in hepatocellular carcinoma following liver transplantation
Circulating citrullinated proteins as candidate liquid biopsy analytes in cancer
Cell-free DNA fragmentomics and epigenomic profiling in hematologic malignancies: current evidence, translational limitations, and future directions
Whole Genome Sequencing-based tumor-informed circulating tumor DNA monitoring for early detection of recurrence in patients with solid tumors
Integrating ctDNA-Based ESR1m Monitoring Into First-Line Care for ER+, HER2- Advanced Breast Cancer: A Consensus Workflow
Decoding coupled epigenetic-fragmentomic signals in circulating cell-free DNA for interpretable cancer diagnosis
Correspondence: Interpreting Hazard Ratios in Meta-Analyses on ctDNA in Colorectal Cancer
Cell-free DNA methylation markers in the diagnosis of hepatitis B virus-related- hepatocellular carcinoma: a review
Integrated Viscoelastic Microfluidics for Label-Free Separation and Concentration of Circulating Tumor Cells
Liquid biopsy cell analysis and ex vivo culture as effective methods of therapeutic indexing of metastasis in B[a]P-induced lung cancer mice for an active targeted quercetin therapy
ctDNA retesting to guide anti-EGFR therapy in later-line metastatic colorectal cancer
Refinement of the UKCGG/CanVIG framework for triage of putative germline variants identified via tumour and ctDNA sequencing: maximising clinical utility and harmonising gene and variant-restricted reporting across UK clinical practice
Multi-institutional study evaluating the role of liquid biopsy to determine risk of extraocular disease, therapy response and recurrence in retinoblastoma
First-Trimester Cell-Free DNA Screening for Common Trisomies Using Rolling-Circle Amplification: A Prospective Study
Real-World Tumor-Informed Circulating Tumor DNA Dynamics and Survival Associations in Advanced Urothelial Cancer Treated With First-Line Enfortumab Vedotin and Pembrolizumab